The plaques harden and narrow the coronary arteries, causing progressive heart tissue damage due to chronic oxygen deprivation. Polyglucosan bodies are composed of large, complex, sugarbased molecules. The study of the cell including its functions, and the changes to it at anytime is critical to understanding any particular disease in a patient. Robbins and cotran pathologic basis of disease, professional edition e book. A systemic approach, eighth edition is todays most comprehensive visual survey of the common diseases affecting each body system. People with apbd typically first experience signs and symptoms related to the condition between ages 35 and 60. The nature of disease pathology for health professions by thomas h. Commentary on the ninth book of medicine dedicated to mansur. Adult polyglucosan body disease apbd is a condition that affects the nervous system. Adult polyglucosan body disease genetics home reference. Adult polyglucosan body disease apbd is characterized by adultonset progressive neurogenic bladder, gait difficulties i.
Pathology is a field of medicine that deals with examination of body organs for the easy diagnosis of the disease. The underlying pathology of coronary artery disease is infiltration of the arteries that supply blood to the heart with fatty deposits called plaques, according to the national heart, lung and blood institute 2. Cardiovascular diseases include conditions that affect the structures or function of your heart or blood vessels. The study of pathology, including the detailed examination of the body.
Textbook of pathology, 6th edition mosc medical college hospital. Microscopically, the pathological hallmark of pd is the presence of abnormal cytoplasmic deposits within neuronal cell bodies which are. This edition has been extensively updated and reorganized to present the fields latest knowledge more efficiently and intuitively than ever. Memmlers the human body in health and disease, 10th ed. Online shopping for books from a great selection of diseases, clinical chemistry. Adult polyglucosan body disease apbd is a lateonset, slowly progressive disorder of the nervous system caused by glycogen branching enzyme gbe deficiency in a subgroup of patients of. Pathology is the study of the causes and effects of disease or injury. I bought this book because i thought that it would complement brs pathology. Learn more about the types and treatments for different cardiovascular diseases. Adult polyglucosan body disease apbd is a rare, genetic disorder characterized by a deficiency of glycogenbranching enzyme, resulting in the accumulation of polyglucosan bodies in muscle, nerve and various other tissues of the body. They have added a chapter entitled the cell as a unit of health and disease at the very beginning of the book.
706 831 1454 1186 239 1165 377 656 258 972 1040 392 711 676 1208 470 807 953 636 843 972 38 865 1267 1005 1023 1622 1265 465 734 1377 677 713 848